The Substance Genre Guide: Story, Cast and Movie Facts
A TMDB-backed guide to The Substance, including cast, release facts, genres and watch-provider notes.
The Substance (2024) — an evergreen reference for this movie: the essentials, the cast, where to watch and what to watch next. Have you ever dreamt of a better version of yourself?
Where to watch
TMDB's U.S. watch-provider data lists HBO Max Amazon Channel, MUBI, MUBI Amazon Channel, HBO Max. Availability changes by country and date, so check your streaming app before watching.
Cast
Demi Moore as Elisabeth; Margaret Qualley as Sue; Dennis Quaid as Harvey; Edward Hamilton-Clark as Fred; Gore Abrams as Oliver; Oscar Lesage as Troy; Christian Erickson as Man at Diner; Robin Greer as Male Nurse
About The Substance
A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
More like The Substance
- Blood Punch
- Infinity Pool
- The Infernal Machine
- The Resurrected
- Repo Men
- Mandy
- Nightmare Cinema
- Southbound
Figures and availability come from public TMDB data and are provided as a sourced reference.
Frequently asked questions
Where can I watch The Substance?
TMDB's U.S. watch-provider data lists HBO Max Amazon Channel, MUBI, MUBI Amazon Channel, HBO Max. Availability changes by country and date, so check your streaming app before watching.
Who is in the cast of The Substance?
Demi Moore as Elisabeth; Margaret Qualley as Sue; Dennis Quaid as Harvey; Edward Hamilton-Clark as Fred; Gore Abrams as Oliver; Oscar Lesage as Troy; Christian Erickson as Man at Diner; Robin Greer as Male Nurse
Is this The Substance guide official?
No. It uses TMDB data as a reference and is not endorsed or certified by TMDB.
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