Best Medicine: Story, Cast and Series Facts
Best Medicine (2026): Drama, Comedy, Medical. Series details, synopsis, cast and season dates from TVmaze.

Story and premise
In Best Medicine a brilliant surgeon leaves Boston to become a small-town doctor where he spent childhood summers. Despite his medical skills, his rude manner alienates locals as he battles hidden phobias and struggles with personal connections.
Series details
- Title: Best Medicine
- Format: Scripted
- Language: English
- Genres: Drama, Comedy, Medical
- Premiere date: 2026-01-04
- Status in TVmaze: Running
- Network listed by TVmaze: FOX
- Network country: United States
- Typical episode runtime: 61 minutes
- TVmaze community rating: 6.2/10
- TVMaze ID: 84556
- IMDb ID: tt36885662
- TVDB ID: 463505
Cast and credited roles
- Josh Charles — Dr. Martin Best
- Abigail Spencer — Louisa Gavin
- Josh Segarra — Sheriff Mark Mylow
- Annie Potts — Aunt Sarah
- Cree — Elaine Denton
- Stephen Spinella — Greg Garrison
- Jason Veasey — George Brady
Seasons in the TVmaze catalogue
- Season 1: premiered 2026-01-04; final listed air date 2026-04-07; episode order: 13.
- Season 2: premiered 2026-09-20; final listed air date 2026-11-03; episode order: 14.
Source and licence
Adapted from Best Medicine on TVmaze. The synopsis is reproduced as plain text; catalogue facts, cast and season records are selected and reformatted. This adapted text is available under CC BY-SA 4.0, following the TVmaze API licence. Network and web-channel credits identify the service listed in this source; they do not establish current streaming availability.



